|Product Overview:||Botulinum Neurotoxin Type B Toxoid was purified from Clostridium botulinum.|
|Description:||Clostridium botulinum neurotoxins (BoNT) are among the most toxic substances known to man. Seven immunologically distinct serotypes of neurotoxin, designated types A through G (BoNT/A, BoNT/B, BoNT/C, BoNT/D, BoNT/E, BoNT/F, BoNT/G), have been identified. These botulinum neurotoxins are naturally produced complexed with one or more nontoxic neurotoxin-associated proteins (NAPs). NAPs are important to toxicity by ingestion in that they protect the neurotoxin from proteases, acidity, heat and they may also play a role in translocation across the mucosal layer.|
|Form:||Each vial when reconstituted with 100 ul of sterile purified water, contains 10.0 ug of botulinum neurotoxin type B toxoid in 0.01 M sodium phosphate, pH 7.5.|
|Notes:||Toxicity: This product is produced from purified botulinum toxin type B by inactivation with formaldehyde. At the highest dose tested (4 ug/mouse) there were no deaths and no signs of illness during seven days of observation.|
|Storage:||Botulinum toxoid type B is supplied as a lyophilized powder, sealed under vacuum. Store at 4 centigrade prior to reconstitution. Following reconstitution, aliquot and freeze. Avoid repeated freezing and thawing.|
|Warning:||Good laboratory technique should be employed in the safe handling of this product. This requlres observing the following practices:
1. Wear appropriate laboratory attire including a lab coat, gloves and safety glasses.
2. Do not mouth pipette, inhale, ingest or allow to come into contact with open wounds. Wash thoroughly any area of the body which comes into contact with the product.
3. Avoid accidental autoinoculation by exercising extreme care when handling in conjunction with any injection device.
4. This product is intended for research purposes by qualified personnel only. It is not intended for use in humans or as a diagnostic agent. Our company is not liable for any damages resulting from the misuse or handling of this product.
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