| Description : |
Galanthus nivalis lectin, unlike most mannose-specific lectins, is not a metalloprotein and does not require Ca2+ or Mn2+ for binding. Binding seems to be preferentially directed toward structures containing (α-1,3) mannose residues. Also in contrast to most mannose-binding lectins, GNL will not bind α-linked glucose. Reports indicate that this lectin binds rat and mouse IgM but not IgG. The only protein from human serum reported to bind to this lectin is α2-macroglobulin. GNL binds to many viral glycoproteins. |
| Source : |
Galanthus nivalis |
| Species : |
Galanthus nivalis |
| Form : |
10 mM HEPES, pH 7.5, 0.15 M NaCl, 0.08% sodium azide, 0.1 mM Ca2+. |
| Bio-activity : |
Inhibiting/Eluting Sugar: 100 mM - 200 mM α-methylmannoside |
| Molecular Mass : |
50 kDa |
| Applications : |
Immunohistochemistry / Immunocytochemistry, Immunofluorescence, Blotting Applications, Elispot, ELISAs, Glycobiology |
| Usage : |
For most applications, we recommend a freshly prepared working solution of 5-20 µg/ml in the above buffer. |
| Storage : |
Refrigerate; for long term storage, aliquots may be stored frozen. If a precipitate forms upon long-term storage, warm to 37 centigrade. and centrifuge before use |
| Concentration : |
2 mg/ml |
| Synonyms : |
Lectin; GNL |
| UniProt ID : |
P30617 |
