Description : |
GSL I is a family of glycoproteins with molecular weights of approximately 114 kDa. There are two types of subunits, termed A and B , with slightly different molecular weights. These subunits combine to form tetrameric structures, resulting in five isolectins. The A -rich lectin preferentially agglutinates blood group A erythrocytes and thus appears to be specific for α-N-acetylgalactosamine residues, while the B -rich lectin preferentially agglutinates blood group B cells and is specific for α-galactose residues. This GSL I is a mixture of the five isolectins. GSL I has been reported to bind several glycoproteins including laminin. |
Source : |
Griffonia Simplicifolia |
Species : |
Griffonia Simplicifolia |
Bio-activity : |
Inhibiting/Eluting Sugar: mixture of 200 mM galactose/200 mM N-acetylgalactosamine. Carbohydrate-Binding Specificity: Galactose, N-Acetylgalactosamine. |
Molecular Mass : |
114 kDa |
Applications : |
Immunohistochemistry / Immunocytochemistry, Immunofluorescence, Blotting Applications, Glycobiology |
Storage : |
Refrigerate in the dark |
Reconstitution : |
Although many buffers can be employed for reconstituting and diluting this lectin, we recommend 10 mM HEPES buffered saline, pH 8.5, 0.1 mM Ca2+. For preserving solutions stored at 4 centigrade, add 0.08% sodium azide to the buffer. |
Synonyms : |
Lectin; GSL I; BSL I |
UniProt ID : |
Q8W1R6 |