|Product Overview:||This product is the Unconjugated Vicia Villosa Lectin and has sugar specificity against N-Acetylgalactosamine.|
|Description:||This lectin is a family of tetrameric glycoproteins consisting of combinations of A and B subunits similar in structure to PHA and GSL I. The dominant isolectins in our preparations appear to be B subunit-rich. VVL recognizes preferentially α- or β-linked terminal N-acetylgalactosamine, especially a single α-N-acetylgalactosamine residue linked to serine or threonine in a polypeptide (the Tn antigen). Evidence suggests that this lectin also may require specific amino acid sequences at the receptor site of glycosylation. The disaccharide galactosyl (α-1,3) N-acetylgalactosamine is also a potent inhibitor of this lectin.|
|Bio-activity:||Inhibiting/Eluting Sugar: 200 mM N-acetylgalactosamine|
|Molecular Mass:||102 kDa - 144 kDa|
|Usage:||Although many buffers can be employed for reconstituting this lectin, we recommend 10 mM HEPES buffered saline, pH 8.5, 0.1 mM Ca2+. For preserving solutions stored at 4 centigrade, 0.8% sodium azide can be used.|
|Synonyms:||Lectin; VVL; VVA|
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