NQO1 Activity Assay Kit
Cat.No. : | Kit-0633 |
Product Overview : | NAD (P)H dehydrogenase [quinone] 1 (NQO1) Activity Assay kit is designed for the sensitive and accurate measurement of NQO1 activity in a number of sample types.NQO1 serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways, NQO1 protects against quinone-induced damage by competing with potentially toxic one-electron pathways. It also functions in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.The enzyme activity is determined by following the reduction of Menadione with cofactor NADH and the simultaneous reduction of WST1 which leads to increased absorbance at 440 nm. |
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Storage : | Store kit at 4ºC immediately upon receipt. |
Size : | 96 tests |
Products Types
◆ Recombinant Protein | ||
NQO1-3717R | Recombinant Rat NQO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NQO1-2909R | Recombinant Rhesus Macaque NQO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NQO1-1534H | Recombinant Human NQO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NQO1-6062H | Recombinant Human NQO1 Protein, GST-tagged | +Inquiry |
NQO1-001H | Active Recombinant Human NQO1 Protein | +Inquiry |
◆ Lysates | ||
NQO1-3725HCL | Recombinant Human NQO1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Ask a questionMutations in NQO1 can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.
The types of mutations in NQO1 include point mutations, insertions/deletions, duplications, etc., which can cause structural and functional abnormalities of the protein.
Abnormal NQO1 levels may indicate cancer, neurodegenerative diseases, and oxidative stress-related diseases.
Studying the regulatory mechanism of NQO1 requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.
This protein can be used as a biomarker in medical treatment to help monitor disease progression and treatment efficacy. In addition, therapeutics targeting NQO1, such as gene therapy or modulating its expression, are also being studied.
NQO1 has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.
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