p53 Translocation Assay Kit (Cell-Based) provides a highly specific p53 primary monoclonal antibody together with a DyLight conjugated secondary antibody in a ready-to-use format. (-)-Nutlin-3, a potent inhibitor of Mdm2-p53 interaction which has been shown to cause the activation and translocation of p53 between the cytoplasm and nuclear compartments, is included as a positive control.
ICC/IF, Functional Studies more details
Reacts with: Human; Predicted to work with: all Mammals
Components: 96 tests; Cell-Based Assay (-)-Nutlin-3 (10 mM): 1 vial; Cell-Based Assay Blocking Solution: 1 vial; Cell-Based Assay Fixative: 1 vial; Cell-Based Assay p53 Total Monoclonal Primary Antibody: 1 vial; DyLight 549-Conjugated Goat Anti-Mouse Secondary Antibody: 1 vial
Compatible Sample Types: