"Protein" Related Products

Plasma Protein Binding Kit

Cat.No.: Kit-0980
Description: A ready-to-use kit to for rapid assessment of drugs candidates' binding to major plasma proteins HSA & AGP.
A novel ready-to-use binding kit designed to assess the binding of drugs to plasma binding protein and mimic the physiological condition of the major plasma proteins human serum albumin (HSA) and a1-acid glycoprotein (AGP). The affinity of a drug candidate to plasma proteins is a true measurement of the free fraction of a drug candidate in plasma.
Features & Benefits: 1. Fast, requiring only 2 minutes for incubation.
2. Accurate. Measures the affinity of the drug candidate to plasma proteins, a true measurement of the free fraction in plasma, capable of producing pharmacological effects.
3. Reliable with highly reproducible results, and robust correlation to equilibrium dialysis method (end-point measurement). Fully quality-controlled plasma protein binding estimates.
4. Relevant. Consists of a mixture of human serum albumin and a1-acid glycoprotein (HSA:AGP = 24:1) a typical physiological ratio of the proteins.
5. Ready-to-use format plated in 96-well or ready-to-use tubes in strips of 8. Kit only requires addition of test material, 2-minute incubation, and quantification.
6. Flexible. Adaptable to automation.

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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