Rac Activation Kit
Cat.No. : | Kit-0757 |
Product Overview : | Rac Activation Kit provides a rapid, cost-effective and reliable tool for detection and semi-quantitative analysis of the cellular activation state of Rac1 and Rac2 G-proteins. If combined with immunological detection of Cdc42, the kit can also detect activated Cdc42-GTP. Please note that this kit provides only an antibody for the detection of Rac1. Active Rac, i. e. Rac complexed to GTP, is purified out of cell extracts via a one-step batch affinity purification step employing GST-PAK-CRIB, an affinity probe that selectively interacts with the active, GTP-bound Rac conformation in loss of the inactive Rac-GDP complex. The kit further includes recombinant Rac1δC-term that serves dual roles: 1. It can be used as western blot control for immunodetection2. Upon loading with GDP or GTP-γ-S (also included in this kit), Rac1δC-GDP or Rac1DC-GTP-γ-S complexes can be used to "spike" cell extracts thus serving as internal assay controls of signal specificity. |
- Specification
- Gene Information
- Related Products
Size : | 1 kit |
Applications : | Functional Studies more details |
Products Types
◆ Assay kits | ||
Kit-0759 | Rac1 Activation Colorimetric Assay Kit (96 assays) | +Inquiry |
Kit-0758 | Rac1 Activation Colorimetric Assay Kit (24 assays) | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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