Recombinant Chicken IL6 Protein
Cat.No. : | IL6-12C |
Product Overview : | Recombinant Chicken IL6 was expressed in Yeast. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is also produced from muscle, and is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. Osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. The role of IL-6 as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10. |
Source : | Yeast |
Species : | Chicken |
Molecular Mass : | The Chicken IL-6 recombinant protein has a predicted molecular weight of 22.0 kDa. |
AA Sequence : | VPLPAAADSS GEVGLEEEAG ARRALLDCEP LARVLRDRAV QLQDEMCKKF TVCENSMEML VRNNLNLPKV TEEDGCLLAG FDEEKCLTKL SSGLFAFQTY LEFIQETFDS EKQNVESLCY STKHLAATIR QMVINPDEVV IPDSAAQKSL LANLKSDKDW IEKITMHLIL RDFTSFMEKT VRAVRYLKKT RSFSA (195) |
Applications : | The Chicken IL-6 endotoxin-free recombinant protein can be used in cell culture, as an IL-6 ELISA Standard, and as a Western Blot Control. |
Publication : |
Isolation and culture of chicken bone marrow-derived CD34+ hematopoietic stem and progenitor cells and induced differentiation to myeloid cells (2023)
|
Gene Name : | IL6 interleukin 6 [ Gallus gallus ] |
Official Symbol : | IL6 |
Synonyms : | IL-6; CHIL-6; interleukin-6 |
Gene ID : | 395337 |
mRNA Refseq : | NM_204628 |
Protein Refseq : | NP_989959 |
UniProt ID : | Q90YI0 |
Products Types
◆ Recombinant Protein | ||
IL6-209H | Recombinant Active Human IL6 Protein, His-tagged(C-ter) | +Inquiry |
IL6-186R | Active Recombinant Rat IL6 Protein | +Inquiry |
IL6-185M | Active Recombinant Mouse IL6 Protein | +Inquiry |
IL6-1179H | Recombinant Human IL6 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL6-1046H | Recombinant Horse IL6 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL6-5224HCL | Recombinant Human IL6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThe dosage and usage of Il6 will vary according to the disease, and generally require individualized regulation by the physician according to the disease situation.
The pharmacokinetic characteristics of Il6 mainly include drug absorption, distribution, metabolism, excretion and other information.
Recombinant Il6 protein has a unique therapeutic advantage in the treatment of multiple myeloma. It can promote the proliferation and differentiation of hematopoietic stem cells and inhibit the growth of tumor cells.
Il6 has specific therapeutic effects for certain diseases, such as rheumatoid arthritis, multiple myeloma and so on.
This protein is widely used in the treatment of rheumatoid arthritis, pneumonia, multiple myeloma, lymphoma, malignant tumors and other diseases.
The effects of Il6 on immune cells are mainly manifested as promoting cell proliferation and differentiation, regulating immune response, etc.
Customer Reviews (3)
Write a reviewAccurate localization and function within the cell.
The binding affinity and affinity constant with the target are high.
Can form a stable micellar structure.
Ask a Question for All IL6 Products
Required fields are marked with *
My Review for All IL6 Products
Required fields are marked with *
Inquiry Basket