Active Recombinant Human Activin A protein
Cat.No. : | Activin A-17H |
Product Overview : | Recombinant Human Activin A was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | Activin A is a TGF-β family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Activin A binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). Activins are homodimers or heterodimers of different β subunits. They are produced as precursor proteins with an amino terminal propeptide that is cleaved to release the C-terminal bioactive ligand. |
Source : | Insect cells |
Species : | Human |
Bio-activity : | Determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg. |
Molecular Mass : | 26.0 kDa |
Protein length : | 116 amino acid residues. |
AA Sequence : | GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV EECGCS |
Purity : | Greater than 95% by SDS-PAGE gel and HPLC analyses. |
Products Types
◆ Recombinant Protein | ||
Activin A-15H | Active Recombinant Human Activin A, His-tagged | +Inquiry |
Activin A-57H | Active Recombinant Human Activin A, CF | +Inquiry |
Activin A-16H | Recombinant Human Activin A protein, His-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket