Recombinant Human ADAM15 Protein, GST-tagged
Cat.No. : | ADAM15-276H |
Product Overview : | Human ADAM15 full-length ORF ( NP_997074.1, 1 a.a. - 772 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 110.1 kDa |
AA Sequence : | MRLALLWALGLLGAGSPLPSWPLPN IGGTEEQQAESEKAPREPLEPQVLQ DDLPISLKKVLQTSLPEPLRIKLEL DGDSHILELLQNRELVPGRPTLVWY QPDGTRVVSEGHTLENCCYQGRVRG YAGSWVSICTCSGLRGLVVLTPERS YTLEQGPGDLQGPPIISRIQDLHLP GHTCALSWRESVHTQKPPEHPLGQR HIRRRRDVVTETKTVELVIVADHSE AQKYRDFQHLLNRTLEVALLLDTFF RPLNVRVALVGLEAWTQRDLVEISP NPAVTLENFLHWRRAHLLPRLPHDS AQLVTGTSFSGPTVGMAIQNSICSP DFSGGVNMDHSTSILGVASSIAHEL GHSLGLDHDLPGNSCPCPGPAPAKT CIMEASTDFLPGLNFSNCSRRALEK ALLDGMGSCLFERLPSLPPMAAFCG NMFVEPGEQCDCGFLDDCVDPCCDS LTCQLRPGAQCASDGPCCQNCQLRP SGWQCRPTRGDCDLPEFCPGDSSQC PPDVSLGDGEPCAGGQAVCMHGRCA SYAQQCQSLWGPGAQPAAPLCLQTA NTRGNAFGSCGRNPSGSYVSCTPRD AICGQLQCQTGRTQPLLGSIRDLLW ETIDVNGTELNCSWVHLDLGSDVAQ PLLTLPGTACGPGLVCIDHRCQRVD LLGAQECRSKCHGHGVCDSNRHCYC EEGWAPPDCTTQLKATSSLTTGLLL SLLVLLVLVMLGASYWYRARLHQRL CQLKGPTCQYSLRGQPSPHPQGSHC LPTPRAGAHRVTCPAQGLESRP |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ADAM15 ADAM metallopeptidase domain 15 [ Homo sapiens ] |
Official Symbol : | ADAM15 |
Synonyms : | ADAM15; ADAM metallopeptidase domain 15; a disintegrin and metalloproteinase domain 15 (metargidin); disintegrin and metalloproteinase domain-containing protein 15; MDC15; metargidin; MDC-15; ADAM 15; metalloprotease RGD disintegrin protein; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15; |
Gene ID : | 8751 |
mRNA Refseq : | NM_003815 |
Protein Refseq : | NP_003806 |
MIM : | 605548 |
UniProt ID : | Q13444 |
Products Types
◆ Recombinant Protein | ||
ADAM15-1186H | Recombinant Human ADAM15 Protein (207-452 aa), GST-tagged | +Inquiry |
ADAM15-1717H | Recombinant Human ADAM15 protein, His-tagged | +Inquiry |
ADAM15-228H | Recombinant Human ADAM15 Protein, His-tagged | +Inquiry |
ADAM15-281H | Active Recombinant Human ADAM15 protein, His-tagged | +Inquiry |
ADAM15-948M | Active Recombinant Mouse ADAM15 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
ADAM15-2808HCL | Recombinant Human ADAM15 cell lysate | +Inquiry |
ADAM15-1820MCL | Recombinant Mouse ADAM15 cell lysate | +Inquiry |
ADAM15-001HCL | Recombinant Human ADAM15 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (4)
Ask a questionADAM15 used in studies of liver and bladder cancers.
We offer MMP9 and MMP2 proteins in addition to ADAM15 proteins.
ADAM15 affects the proliferation of H460 cells by regulating PI3K-AKT and MAPK-ERK signaling pathways.
Addition of GST tags can accelerate the solubilization of certain insoluble proteins.
Customer Reviews (2)
Write a reviewThe purchased protein is suitable for WB experiments and I am satisfied with the results.
The technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
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