Active Recombinant Human AKT2 Protein, GST-His tagged

• Cat.No.: AKT2-424H
• Product Overview: Human AKT2 (NM_001626.2, 107 a.a. - 481 a.a.) partial recombinant protein with GST-His tag expressed in Sf9 cells.

Specification

• Description: This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]
• Source: Insect Cell
• Species: Human
• Tag: GST-His
• Form: Liquid
• Bio-activity: 272 pmol/μg x min
• Molecular Mass: 72.844 kDa
• Applications: Functional Study; SDS-PAGE
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: 0.367 ug/uL
• Storage Buffer: In 50 mM Tris-HCl, 100 mM NaCl, pH 8.0. (5 mM DTT, 15 mM reduced glutathione, 20% glycerol)

Gene Information

• Gene Name: AKT2 v-akt murine thymoma viral oncogene homolog 2 [ Homo sapiens ]
• Official Symbol: AKT2
• Synonyms: AKT2; v-akt murine thymoma viral oncogene homolog 2; RAC-beta serine/threonine-protein kinase; PKB beta; RAC-PK-beta; protein kinase Akt-2; protein kinase B beta; rac protein kinase beta; murine thymoma viral (v-akt) homolog-2; PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA
• Gene ID: 208
• mRNA Refseq: NM_001243027
• Protein Refseq: NP_001229956
• MIM: 164731
• UniProt ID: P31751