Recombinant Human ALDH1A1 Protein, GST-tagged

• Cat.No.: ALDH1A1-437H
• Product Overview: Human ALDH1A1 full-length ORF ( AAH01505, 1 a.a. - 501 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 80.63 kDa
• AA Sequence: MSSSGTPDLPVLLTDLKIQYTKIFI NNEWHDSVSGKKFPVFNPATEEELC QVEEGDKEDVDKAVKAARQAFQIGS PWRTMDASERGRLLYKLADLIERDR LLLATMESMNGGKLYSNAYLNDLAG CIKTLRYCAGWADKIQGRTIPIDGN FFTYTRHEPIGVCGQIIPWNFPLVM LIWKIGPALSCGNTVVVKPAEQTPL TALHVASLIKEAGFPPGVVNIVPGY GPTAGAAISSHMDIDKVAFTGSTEV GKLIKEAAGKSNLKRVTLELGGKSP CIVLADADLDNAVEFAHHGVFYHQG QCCIAASRIFVEESIYDEFVRRSVE RAKKYILGNPLTPGVTQGPQIDKEQ YDKILDLIESGKKEGAKLECGGGPW GNKGYFVQPTVFSNVTDEMRIAKEE IFGPVQQIMKFKSLDDVIKRANNTF YGLSAGVFTKDIDKAITISSALQAG TVWVNCYGVVSAQCPFGGFKMSGNG RELGEYGFHEYTEVKTVTVKISQKN S
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ALDH1A1 aldehyde dehydrogenase 1 family, member A1 [ Homo sapiens ]
• Official Symbol: ALDH1A1
• Synonyms: ALDH1A1; aldehyde dehydrogenase 1 family, member A1; ALDH1, PUMB1; retinal dehydrogenase 1; RALDH1; retinaldehyde dehydrogenase 1; ALHDII; RALDH 1; ALDH class 1; acetaldehyde dehydrogenase 1; aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase, liver cytosolic; ALDC; ALDH1; PUMB1; ALDH11; ALDH-E1; MGC2318
• Gene ID: 216
• mRNA Refseq: NM_000689
• Protein Refseq: NP_000680
• MIM: 100640
• UniProt ID: P00352