Recombinant Human ALOX12 Protein, GST-tagged

• Cat.No.: ALOX12-482H
• Product Overview: Human ALOX12 full-length ORF ( NP_000688.1, 1 a.a. - 663 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: ALOX12 (Arachidonate 12-Lipoxygenase, 12S Type) is a Protein Coding gene. Diseases associated with ALOX12 include Inflammatory Bowel Disease 12 and Colorectal Cancer 12. Among its related pathways are Arachidonic acid metabolism and HETE and HPETE biosynthesis and metabolism. GO annotations related to this gene include iron ion binding and arachidonate 12-lipoxygenase activity. An important paralog of this gene is ALOX15.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 102.1 kDa
• AA Sequence: MGRYRIRVATGAWLFSGSYNRVQLW LVGTRGEAELELQLRPARGEEEEFD HDVAEDLGLLQFVRLRKHHWLVDDA WFCDRITVQGPGACAEVAFPCYRWV QGEDILSLPEGTARLPGDNALDMFQ KHREKELKDRQQIYCWATWKEGLPL TIAADRKDDLPPNMRFHEEKRLDFE WTLKAGALEMALKRVYTLLSSWNCL EDFDQIFWGQKSALAEKVRQCWQDD ELFSYQFLNGANPMLLRRSTSLPSR LVLPSGMEELRAQLEKELQNGSLFE ADFILLDGIPANVIRGEKQYLAAPL VMLKMEPNGKLQPMVIQIQPPNPSS PTPTLFLPSDPPLAWLLAKSWVRNS DFQLHEIQYHLLNTHLVAEVIAVAT MRCLPGLHPIFKFLIPHIRYTMEIN TRARTQLISDGGIFDKAVSTGGGGH VQLLRRAAAQLTYCSLCPPDDLADR GLLGLPGALYAHDALRLWEIIARYV EGIVHLFYQRDDIVKGDPELQAWCR EITEVGLCQAQDRGFPVSFQSQSQL CHFLTMCVFTCTAQHAAINQGQLDW YAWVPNAPCTMRMPPPTTKEDVTMA TVMGSLPDVRQACLQMAISWHLSRR QPDMVPLGHHKEKYFSGPKPKAVLN QFRTDLEKLEKEITARNEQLDWPYE YLKPSCIENSVTI
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ALOX12 arachidonate 12-lipoxygenase [ Homo sapiens ]
• Official Symbol: ALOX12
• Synonyms: ALOX12; arachidonate 12-lipoxygenase; arachidonate 12-lipoxygenase, 12S-type; 12S LOX; platelet 12 LOX; platelet 12-LOX; 12S-lipoxygenase; 12(S)-lipoxygenase; platelet-type 12-lipoxygenase; platelet-type lipoxygenase 12; LOG12; 12-LOX; 12S-LOX
• Gene ID: 239
• mRNA Refseq: NM_000697
• Protein Refseq: NP_000688
• MIM: 152391
• UniProt ID: P18054