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Recombinant Human ALOX5AP Protein, GST-tagged

Cat.No. : ALOX5AP-488H
Product Overview : Human ALOX5AP full-length ORF ( AAH18538, 1 a.a. - 161 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 43.45 kDa
AA Sequence : MDQETVGNVVLLAIVTLISVVQNGF FAHKVEHESRTQNGRSFQRTGTLAF ERVYTANQNCVDAYPTFLAVLWSAG LLCSQVPAAFAGLMYLFVRQKYFVG YLGERTQSTPGYIFGKRIILFLFLM SVAGIFNYYLIFFFGSDFENYIKTI STTISPLLLIP
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ALOX5AP arachidonate 5-lipoxygenase-activating protein [ Homo sapiens ]
Official Symbol : ALOX5AP
Synonyms : ALOX5AP; arachidonate 5-lipoxygenase-activating protein; five lipoxygenase activating protein; FLAP; MK 886 binding protein; MK-886-binding protein;
Gene ID : 241
mRNA Refseq : NM_001204406
Protein Refseq : NP_001191335
MIM : 603700
UniProt ID : P20292

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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