Recombinant Human ALPL Protein, His-tagged
Cat.No. : | ALPL-386H |
Product Overview : | Recombinant Human ALPL(Leu18-Ser502), transcript variant 1, fused with His tag at N-terminal was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. |
Source : | HEK293 cells |
Tag : | His |
Form : | 20mM HEPES, 150mM NaCl, 2mM MgSO4, 0.1mM ZnCl2, pH 7.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. |
Molecular Mass : | 54.5 kDa |
Endotoxin : | < 0.1 EU per µg protein as determined by LAL test |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | ALPL alkaline phosphatase, liver/bone/kidney [ Homo sapiens ] |
Official Symbol : | ALPL |
Synonyms : | ALPL; alkaline phosphatase, liver/bone/kidney; HOPS; alkaline phosphatase, tissue-nonspecific isozyme; TNSALP; glycerophosphatase; tissue-nonspecific ALP; alkaline phosphomonoesterase; liver/bone/kidney-type alkaline phosphatase; alkaline phosphatase liver/bone/kidney isozyme; TNAP; APTNAP; AP-TNAP; FLJ40094; FLJ93059; MGC161443; MGC167935; |
Gene ID : | 249 |
mRNA Refseq : | NM_000478 |
Protein Refseq : | NP_000469 |
MIM : | 171760 |
UniProt ID : | P05186 |
Products Types
◆ Recombinant Protein | ||
ALPL-2458H | Recombinant Human ALPL Protein, His (Fc)-Avi-tagged | +Inquiry |
ALPL-001H | Recombinant Human ALPL Protein, His-tagged | +Inquiry |
ALPL-028H | Recombinant Human ALPL Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
ALPL-297R | Recombinant Rat ALPL Protein, His (Fc)-Avi-tagged | +Inquiry |
Alpl-487M | Recombinant Mouse Alpl Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
ALPL-5324H | Active Native Human Alkaline Phosphatase | +Inquiry |
ALPL-66C | Active Native Calf Alkaline Phosphatase | +Inquiry |
ALPL-8004H | Native Human Liver Alkaline Phosphatase | +Inquiry |
◆ Lysates | ||
ALPL-3092HCL | Recombinant Human ALPL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket