Recombinant Human ANGPT2 protein, GST-tagged

• Cat.No.: ANGPT2-551H
• Product Overview: Human ANGPT2 full-length ORF (BAG35440.1, 1 a.a. - 496 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 80.96 kDa
• AA Sequence: MWQIVFFTLSCDLVLAAAYNNFRKS MDSIGKKQYQVQHGSCSYTFLLPEM DNCRSSSSPYVSNAVQRDAPLEYDD SVQRLQVLENIMENNTQWLMKLENY IQDNMKKEMVEIQQNAVQNQTAVMI EIGTNLLNQTAEQTRKLTDVEAQVL NQTTRLELQLLEHSLSTNKLGKQIL DQTSEINKFQDKNSFLEKKVLAMED KHIIQLQSIKEEKDQLQVLVSKQNS IIEELEKKIVTATVNNSVLQKQQHD LMETVNNLLTMMSTSNSAKDPTVAK EEQISFRDCAEVFKSGHTTNGIYTL TFPNSTEEIKAYCDMEAGGGGWTII QRREDGSVDFQRTWKEYKVGFGNPS GEYWLGNEFVSQLTNQQRYVLKIHL KDWEGNEAYSLYEHFYLSSEELNYR IHLKGLTGTAGKISSISQPGNDFST KDGDNDKCICKCSQMLTGGWWFDAC GPSNLNGMYYPQRQNTNKFNGIKWY YWKGSGYSLKATTMMIRPADF
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ANGPT2 angiopoietin 2 [ Homo sapiens ]
• Official Symbol: ANGPT2
• Synonyms: ANGPT2; angiopoietin 2; angiopoietin-2; Ang2; ANG-2; Tie2-ligand; angiopoietin-2B; angiopoietin-2a; ANG2; AGPT2
• Gene ID: 285
• mRNA Refseq: NM_001118887
• Protein Refseq: NP_001112359
• MIM: 601922
• UniProt ID: O15123