Recombinant Human ANGPTL8 protein

• Cat.No.: ANGPTL8-190H
• Product Overview: Recombinant human Betatrophin cDNA ( 177aa ) was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Form: 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, Sucrose and DTT.
• AA Sequence: MTLHRNEYGIASILDSYQCTAEISL ADLATIFFAQFVQEATYKEVSKMVK DALTAIEKPTGDEQSSGCLENQLPA FLEELCHEKEILEKYGHSDCCSQSE EGRHNCFLAHKKPTPASIPLFQVPE PVTSCEAYEEDRETFMNKFIYEIAR RHPFLYAPTILLWAARYDKIIPSCC KAENAVECFQTKAATVTKELRESSG GSHHHHHHGSENLYFQGAPMGGPEL AQHEELTLLFHGTLQLGQALNGVYR TTEGRLTKARNSLGLYGRTIELLGQ EVSRGRDAAQELRASLLETQMEEDI LQLQAEATAEVLGEVAQAQKVLRDS VQRLEVQLRSAWLGPAYREFEVLKA HADKQSHILWALTGHVQRQRREMVA QQHRLRQIQERLHTAALPA
• Purity: >90% by SDS-PAGE
• Applications: 1. May be used for in vitro human Betatrophin signaling pathway regulation study for human pancreatic beta cell differentiation.2. As antigen for specific antibody production.
• Storage: Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days.
• Publication:
  Recombinant betatrophin (Angptl‑8/lipasin) ameliorates streptozotocin‑induced hyperglycemia and β‑cell destruction in neonatal rats (2019)

Gene Information

• Gene Name: ANGPTL8 angiopoietin like 8 [ Homo sapiens ]
• Official Symbol: ANGPTL8
• Synonyms: RIFL; TD26; PRO1185; PVPA599; C19orf80; angiopoietin-like 8; betatrophin variant 1; betatrophin variant 2; hepatocellular carcinoma-associated gene TD26; hepatocellular carcinoma-associated protein TD26; lipasin; refeeding-induced fat and liver protein
• Gene ID: 55908
• mRNA Refseq: NM_018687
• Protein Refseq: NP_061157
• MIM: 616223
• UniProt ID: Q6UXH0
• Chromosome Location: 19p13.2
• Function: hormone activity; hormone activity; protein binding