Recombinant Human AP3M1 protein, GST-tagged

• Cat.No.: AP3M1-657H
• Product Overview: Human AP3M1 full-length ORF ( NP_036227.1, 1 a.a. - 418 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 73.3 kDa
• AA Sequence: MIHSLFLINCSGDIFLEKHWKSVVS QSVCDYFFEAQEKAADVENVPPVIS TPHHYLISIYRDKLFFVSVIQTEVP PLFVIEFLHRVADTFQDYFGECSEA AIKDNVVIVYELLEEMLDNGFPLAT ESNILKELIKPPTILRSVVNSITGS SNVGDTLPTGQLSNIPWRRAGVKYT NNEAYFDVVEEIDAIIDKSGSTVFA EIQGVIDACIKLSGMPDLSLSFMNP RLLDDVSFHPCIRFKRWESERVLSF IPPDGNFRLISYRVSSQNLVAIPVY VKHSISFKENSSCGRFDITIGPKQN MGKTIEGITVTVHMPKVVLNMNLTP TQGSYTFDPVTKVLTWDVGKITPQK LPSLKGLVNLQSGAPKPEENPSLNI QFKIQQLAISGLKVNRLDMYGEKYK PFKGVKYVTKAGKFQVRT
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: AP3M1 adaptor-related protein complex 3, mu 1 subunit [ Homo sapiens ]
• Official Symbol: AP3M1
• Synonyms: AP3M1; adaptor-related protein complex 3, mu 1 subunit; AP-3 complex subunit mu-1; mu3A-adaptin; mu-adaptin 3A; AP-3 adapter complex mu3A subunit; clathrin adaptor complex AP3, mu-3A subunit; adapter-related protein complex 3 mu-1 subunit; MGC22164
• Gene ID: 26985
• mRNA Refseq: NM_012095
• Protein Refseq: NP_036227
• MIM: 610366
• UniProt ID: Q9Y2T2