Recombinant Human APOA1 protein, GST-tagged

• Cat.No.: APOA1-689H
• Product Overview: Human APOA1 full-length ORF ( AAH05380, 1 a.a. - 267 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 55.11 kDa
• AA Sequence: MKAAVLTLAVLFLTGSQARHFWQQD EPPQSPWDRVKDLATVYVDVLKDSG RDYVSQFEGSALGKQLNLKLLDNWD SVTSTFSKLREQLGPVTQEFWDNLE KETEGLRQEMSKDLEEVKAKVQPYL DDFQKKWQEEMELYRQKVEPLRAEL QEGARQKLHELQEKLSPLGEEMRDR ARAHVDALRTHLAPYSDELRQRLAA RLEALKENGGARLAEYHAKATEHLS TLSEKAKPALEDLRQGLLPVLESFK VSFLSALEEYTKKLNTQ
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: APOA1 apolipoprotein A-I [ Homo sapiens ]
• Official Symbol: APOA1
• Synonyms: APOA1; apolipoprotein A-I; apo-AI; apoA-I; MGC117399
• Gene ID: 335
• mRNA Refseq: NM_000039
• Protein Refseq: NP_000030
• MIM: 107680
• UniProt ID: P02647