Recombinant Human ATIC protein, GST-tagged
Cat.No. : | ATIC-952H |
Product Overview : | Human ATIC full-length ORF ( NP_004035.2, 1 a.a. - 592 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 91 kDa |
AA Sequence : | MAPGQLALFSVSDKTGLVEFARNLT ALGLNLVASGGTAKALRDAGLAVRD VSELTGFPEMLGGRVKTLHPAVHAG ILARNIPEDNADMARLDFNLIRVVA CNLYPFVKTVASPGVTVEEAVEQID IGGVTLLRAAAKNHARVTVVCEPED YVVVSTEMQSSESKDTSLETRRQLA LKAFTHTAQYDEAISDYFRKQYSKG VSQMPLRYGMNPHQTPAQLYTLQPK LPITVLNGAPGFINLCDALNAWQLV KELKEALGIPAAASFKHVSPAGAAV GIPLSEDEAKVCMVYDLYKTLTPIS AAYARARGADRMSSFGDFVALSDVC DVPTAKIISREVSDGIIAPGYEEEA LTILSKKKNGNYCVLQMDQSYKPDE NEVRTLFGLHLSQKRNNGVVDKSLF SNVVTKNKDLPESALRDLIVATIAV KYTQSNSVCYAKNGQVIGIGAGQQS RIHCTRLAGDKANYWWLRHHPQVLS MKFKTGVKRAEISNAIDQYVTGTIG EDEDLIKWKALFEEVPELLTEAEKK EWVEKLTEVSISSDAFFPFRDNVDR AKRSGVAYIAAPSGSAADKVVIEAC DELGIILAHTNLRLFHH |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [ Homo sapiens ] |
Official Symbol : | ATIC |
Synonyms : | ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; bifunctional purine biosynthesis protein PURH; AICARFT; IMPCHASE; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PURH; AICARFT/IMPCHASE; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AICAR; FLJ93545; |
Gene ID : | 471 |
mRNA Refseq : | NM_004044 |
Protein Refseq : | NP_004035 |
MIM : | 601731 |
UniProt ID : | P31939 |
Products Types
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◆ Lysates | ||
ATIC-8618HCL | Recombinant Human ATIC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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