Recombinant Human ATP1B1 protein, GST-tagged

• Cat.No.: ATP1B1-965H
• Product Overview: Human ATP1B1 full-length ORF ( AAH00006, 1 a.a. - 303 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 58.96 kDa
• AA Sequence: MARGKAKEEGSWKKFIWNSEKKEFL GRTGGSWFKILLFYVIFYGCLAGIF IGTIQVMLLTISEFKPTYQDRVAPP GLTQIPQIQKTEISFRPNDPKSYEA YVLNIVRFLEKYKDSAQRDDMIFED CGDVPSEPKERGDFNHERGERKVCR FKLEWLGNCSGLNDETYGYKEGKPC IIIKLNRVLGFKPKPPKNESLETYP VMKYNPNVLPVQCTGKRDEDKDKVG NVEYFGLGNSPGFPLQYYPYYGKLL QPKYLQPLLAVQFTNLTMDTEIRIE CKAYGENIGYSEKDRFQGRFDVKIE VKS
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide [ Homo sapiens ]
• Official Symbol: ATP1B1
• Synonyms: ATP1B1; ATPase, Na+/K+ transporting, beta 1 polypeptide; ATP1B; sodium/potassium-transporting ATPase subunit beta-1; adenosinetriphosphatase; Na, K-ATPase beta-1 polypeptide; Beta 1-subunit of Na(+),K(+)-ATPase; sodium/potassium-dependent ATPase beta-1 subunit; sodium/potassium-transporting ATPase beta-1 chain; MGC1798
• Gene ID: 481
• mRNA Refseq: NM_001677
• Protein Refseq: NP_001668
• MIM: 182330
• UniProt ID: P05026