Recombinant Human AURKB/INCENP protein, Flag/His-tagged, Biotinylated

• Cat.No.: AURKB-35H
• Product Overview: Recombinant Human AurB [1-344(end) amino acids of accession number Q96GD4] fused with DYKDDDDK tag at N-terminal and biotinylated was co-expressed with His-tagged INCENP(INBOX) [803-918(end) amino acids of accession number AAU04398] in insect cell.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag/His
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: AURKB(43 kDa)
• Purity: >82% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: AURKB aurora kinase B [ Homo sapiens ]
• Official Symbol: AURKB
• Synonyms: AURKB; Aik2; AIM 1; ARK2; AurB; aurora 1; aurora B; IPL1; PPP1R48; STK5; ARK-2; STK-1; aurora-1; aurora-B; AIK2; AIM1; AIM-1; STK12
• Gene ID: 9212
• mRNA Refseq: NM_001256834
• Protein Refseq: NP_001243763
• MIM: 604970
• UniProt ID: Q96GD4
• Chromosome Location: 17p13.1
• Pathway: APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Aurora A signaling, organism-specific biosystem; Aurora B signaling, organism-specific biosystem; Aurora C signaling, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem
• Function: ATP binding; metal ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity