Recombinant Human BCR Protein, GST-tagged
Cat.No. : | BCR-177H |
Product Overview : | Human BCR partial ORF ( NP_004318.3, 182 a.a. - 280 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 36.63 kDa |
AA Sequence : | FHHERGLVKVNDKEVSDRISSLGSQ AMQMERKKSQHGAGSSVGDASRPPY RGRSSESSCGVDGDYEDAELNPRFL KDNLIDANGGSRPPWPPLEYQPYQ |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | BCR breakpoint cluster region [ Homo sapiens ] |
Official Symbol : | BCR |
Synonyms : | BCR; breakpoint cluster region; BCR1, D22S11; breakpoint cluster region protein; ALL; CML; D22S662; PHL; renal carcinoma antigen NY-REN-26; BCR1; D22S11; FLJ16453; |
Gene ID : | 613 |
mRNA Refseq : | NM_004327 |
Protein Refseq : | NP_004318 |
MIM : | 151410 |
UniProt ID : | P11274 |
Products Types
◆ Recombinant Protein | ||
Bcr-463M | Recombinant Mouse Bcr Protein, MYC/DDK-tagged | +Inquiry |
BCR-2637H | Recombinant Human BCR protein(161-260 aa), C-His-tagged | +Inquiry |
BCR-558H | Recombinant Human BCR Protein, His-tagged | +Inquiry |
Bcr-559M | Recombinant Mouse Bcr Protein, His-tagged | +Inquiry |
BCR-10196H | Recombinant Human BCR, His-tagged | +Inquiry |
◆ Lysates | ||
BCR-166HCL | Recombinant Human BCR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket