Recombinant Human BGLAP protein, GST-tagged
Cat.No. : | BGLAP-1474H |
Product Overview : | Recombinant Human BGLAP(1 a.a. - 100 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Form : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Molecular Mass : | 37.4 kDa |
AA Sequence : | MRALTLLALLALAALCIAGQAGAKP SGAESSKGAAFVSKQEGSEVVKRPR RYLYQWLGAPVPYPDPLEPRREVCE LNPDCDELADHIGFQEAYRRFYGPV |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Gene Name : | BGLAP bone gamma-carboxyglutamate (gla) protein [ Homo sapiens ] |
Official Symbol : | BGLAP |
Synonyms : | BGLAP; bone gamma-carboxyglutamate (gla) protein; osteocalcin; bone Gla protein; gamma-carboxyglutamic acid-containing protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); OC; BGP; |
Gene ID : | 632 |
mRNA Refseq : | NM_199173 |
Protein Refseq : | NP_954642 |
MIM : | 112260 |
UniProt ID : | P02818 |
Chromosome Location : | 1q25-q31 |
Pathway : | Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; FGF signaling pathway, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; M Phase, organism-specific biosystem; Mitotic M-M/G1 phases, organism-specific biosystem; |
Function : | calcium ion binding; hydroxyapatite binding; structural constituent of bone; structural molecule activity; |
Products Types
◆ Recombinant Protein | ||
BGLAP-634R | Recombinant Rat BGLAP Protein, His (Fc)-Avi-tagged | +Inquiry |
Bglap-1143R | Recombinant Rat Bglap Protein, GST-tagged | +Inquiry |
BGLAP-2543H | Recombinant Human BGLAP Protein, His (Fc)-Avi-tagged | +Inquiry |
Bglap-707M | Recombinant Mouse Bglap Protein, MYC/DDK-tagged | +Inquiry |
Bglap-1262M | Recombinant Mouse Bglap Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
BGLAP-57H | Native Human Osteocalcin | +Inquiry |
BGLAP-60H | Native Human BGLAP protein | +Inquiry |
BGLAP-59B | Native Bovine Osteocalcin | +Inquiry |
◆ Lysates | ||
BGLAP-8460HCL | Recombinant Human BGLAP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Write a reviewThis assurance enables me to confidently utilize the BGLAP protein in my research, knowing that it will consistently deliver reliable and accurate results.
The manufacturer plays a crucial role in supporting my research with their extensive expertise and resources.
By using BGLAP protein, I can gain insights into the underlying molecular processes contributing to amyloidosis, which can ultimately aid in the development of novel therapeutic strategies.
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