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Recombinant Human BMP2 protein, His & GST-tagged

Cat.No. : BMP2-560H
Product Overview : Recombinant Human BMP2 (P12643) aa. (Gln283~Arg396) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Source : E. coli
Species : Human
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : 43kDa as determined by SDS-PAGE reducing conditions.
Protein length : Gln283~Arg396
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 97%
Characteristic : The isoelectric point is 7.3.
Applications : SDS-PAGE; WB; ELISA; IP; CoIP; ReporterAssays; Purification; Amine Reactive Labeling.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Concentration : 200µg/mL
Storage buffer : PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300
Reconstitution : Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : BMP2 bone morphogenetic protein 2 [ Homo sapiens (human) ]
Official Symbol : BMP2
Synonyms : BMP2; bone morphogenetic protein 2; BDA2; BMP2A; bone morphogenetic protein 2A
Gene ID : 650
mRNA Refseq : NM_001200.3
Protein Refseq : NP_001191.1
UniProt ID : P12643

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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05/06/2023

    We have tested the recombinant protein in our ELISAs and it performs well.

    02/01/2023

      I'm pleased with your recombinant products. It is done well in our experiment.

      01/29/2023

        Very nice puchase experience with all of you.

        08/06/2022

          I’ve used the products you provided, and they all work good in my study.

          04/09/2021

            Thanks so much! Your protein performed really well,

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