| Description : |
This gene is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation. Two transcript variants encoding different isoforms have been found for this gene. |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
100.3 kDa |
| AA Sequence : |
MKKFSRMPKSEGGSGGGAAGGGAGG AGAGAGCGSGGSSVGVRVFAVGRHQ VTLEESLAEGGFSTVFLVRTHGGIR CALKRMYVNNMPDLNVCKREITIMK ELSGHKNIVGYLDCAVNSISDNVWE VLILMEYCRAGQVVNQMNKKLQTGF TEPEVLQIFCDTCEAVARLHQCKTP IIHRDLKVENILLNDGGNYVLCDFG SATNKFLNPQKDGVNVVEEEIKKYT TLSYRAPEMINLYGGKPITTKADIW ALGCLLYKLCFFTLPFGESQVAICD GNFTIPDNSRYSRNIHCLIRFMLEP DPEHRPDIFQVSYFAFKFAKKDCPV SNINNSSIPSALPEPMAASEAAARK SQIKARITDTIGPTETSIAPRQRPK ANSATTATPSVLTIQSSATPVKVLA PGEFSNHRPKGALRPGNGPEILLGQ GPPQQPPQQHRVLQQLQQGDWRLQQ LHLQHRHPHQQQQQQQQQQQQQQQQ QQRQQQQQQQQHHHHHHHHLLQDAY MQQYQHATQQQQMLQQQFLMHSVYQ PQPSASQYPTMMPQYQQAFFQQQML AQHQPSQQQASPEYLTSPQEFSPAL VSYTSSLPAQVGTIMDSSYSANRSV ADKEAIANFTNQKNISNPPDMSGWN PFGEDNFSKLTEEELLDREFDLLRS SKGHLKAYFASQ |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
