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Recombinant Human BMP4 Protein, GST-tagged

Cat.No. : BMP4-266H
Product Overview : Human BMP4 (NP_001193.1, 25 a.a. - 408 a.a.) partial recombinant protein with His-MBP tag expressed in Escherichia coli.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5 untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Source : E. coli
Species : Human
Tag : GST
Form : In 20 mM sodium phosphate, 0.5 M NaCl, 0,5 M imidazole, pH 7.4. (30% glycerol)
Molecular Mass : 90.266 kDa
Endotoxin : < 0.1 EU per ug of the protein
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : In 20 mM sodium phosphate, 0.5 M NaCl, 0,5 M imidazole, pH 7.4. (30% glycerol)
Gene Name : BMP4 bone morphogenetic protein 4 [ Homo sapiens ]
Official Symbol : BMP4
Synonyms : BMP4; bone morphogenetic protein 4; BMP2B; BMP-4; BMP-2B; bone morphogenetic protein 2B; ZYME; OFC11; BMP2B1; MCOPS6;
Gene ID : 652
mRNA Refseq : NM_001202
Protein Refseq : NP_001193
MIM : 112262
UniProt ID : P12644

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is BMP4 applied in spinal fusion surgery? 03/30/2022

BMP4 can be used in spinal fusion surgery to stimulate bone growth and fuse vertebrae together, which can alleviate back pain and stabilize the spine.

Are there any genetic disorders related to BMP4? 07/03/2020

Mutations in BMP4 or its receptors can lead to congenital disorders, such as orofacial clefts and heart defects.

Are there ongoing clinical trials involving BMP4 in regenerative medicine? 07/12/2019

Yes, there are ongoing trials exploring the use of BMP4 in regenerative medicine for conditions like osteoarthritis and tendon injuries.

Are there any potential risks or side effects associated with the clinical use of BMP4? 06/11/2018

Yes, some risks include excessive bone growth, swelling, and inflammation at the application site. These complications can be carefully managed by healthcare providers.

Can BMP4 be used in cosmetic surgery? 02/10/2017

Yes, BMP4 can be used to aid in tissue regeneration in cosmetic procedures, such as in the reconstruction of facial bone defects or enhancement of soft tissue volume.

Customer Reviews (3)

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Reviews
11/22/2020

    The BMP4 protein is a valuable resource for researchers due to its high quality and its ability to meet specific experimental needs.

    08/26/2020

      the manufacturer's technical support team can offer prompt assistance in case any issues arise during the handling or application of the BMP4 protein.

      06/05/2018

        The manufacturer's support can play a crucial role in assisting researchers throughout their trials.

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