Recombinant Human BRD8 protein

• Cat.No.: BRD8-25H
• Product Overview: Recombinant Human BRD8(701-819 aa) was expressed in E. coli.

Specification

• Description: The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Multiple alternatively spliced transcript variants that encode distinct isoforms have been identified.
• Source: E. coli
• Species: Human
• Form: 1.91 μg/μL in 50 mM Tris HCl, pH 7.5, 500 mM NaCl, 1 mM TCEP, 10 % glycerol as determined by OD280.
• Molecular Mass: 14.1 kDa
• Protein length: 701-819 aa
• Purity: >90% by SDS-PAGE
• Storage: Store at -70 centigrade. Thaw quickly and store on ice before use. The remaining, unused, undiluted protein should be snap frozen, for example in a dry/ice ethanol bath or liquid nitrogen. Minimize freeze/thaws if possible, but very low volume aliquots (<

Gene Information

• Gene Name: BRD8 bromodomain containing 8 [ Homo sapiens ]
• Official Symbol: BRD8
• Synonyms: BRD8; bromodomain containing 8; bromodomain-containing protein 8; p120; SMAP; trCP120; skeletal muscle abundant protein 2; thyroid hormone receptor coactivating protein of 120 kDa; SMAP2
• Gene ID: 10902
• mRNA Refseq: NM_139199
• Protein Refseq: NP_631938
• MIM: 602848
• UniProt ID: Q9H0E9
• Chromosome Location: 5q31
• Function: sequence-specific DNA binding transcription factor activity; thyroid hormone receptor activity