| Description : |
This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer. |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
145.09 kDa |
| AA Sequence : |
MDTPENVLQMLEAHMQSYKGNDPLG VWERYIQWVEENFPENKEYLITLLE HLMKEFLDKKKYHNDPRFISYCLKF AEYNSDLRQFFEFLYNHGIGTLSSP LYIAWAGHLEAQGELQHASAVLQRG IQNQAEPREFLQQQYRLFQTRLTET HLPAQARTSEPLHNVQVLNQMITSK SNPGNNMACISKNQGSELSGVISSA CDKESNMERRVITISKSEYSVHSSL ASKVDVEQVVMYCKEKLIRGESEFS FEELRAQKYNQRRKHEQWVNEDRHY MKRKEANAFEEQLLKQKMDELHKKL HQVVETSHEDLPASQERSEVNPARM GPSVGSQQELRAPCLPVTYQQTPVN MEKNPREAPPVVPPLANAISAALVS PATSQSIAPPVPLKAQTVTDSMFAV ASKDAGCVNKSTHEFKPQSGAEIKE GCETHKVANTSSFHTTPNTSLGMVQ ATPSKVQPSPTVHTKEALGFIMNMF QAPTLPDISDDKDEWQSLDQNEDAF EAQFQKNVRSSGAWGVNKIISSLSS AFHVFEDGNKENYGLPQPKNKPTGA RTFGERSVSRLPSKPKEEVPHAEEF LDDSTVWGIRCNKTLAPSPKSPGDF TSAAQLASTPFHKLPVESVHILEDK ENVVAKQCTQATLDSCEENMVVPSR DGKFSPIQEKSPKQALSSHMYSASL LRLSQPAAGGVLTCEAELGVEACRL TDTDAAIAEDPPDAIAGLQAEWMQM SSLGTVDAPNFIVGNPWDDKLIFKL LSGLSKPVSSYPNTFEWQCKLPAIK PKTEFQLGSKLVYVHHLLGEGAFAQ VYEATQGDLNDAKNKQKFVLKVQKP ANPWEFYIGTQLMERLKPSMQHMFM KFYSAHLFQNGSVLVGELYSYGTLL NAINLYKNTPEKVMPQGLVISFAMR MLYMIEQVHDCEIIHGDIKPDNFIL GNGFLEQDDEDDLSAGLALIDLGQS IDMKLFPKGTIFTAKCETSGFQCVE MLSNKPWNYQIDYFGVAATVYCMLF GTYMKVKNEGGECKPEGLFRRLPHL DMWNEFFHVMLNIPDCHHLPSLDLL RQKLKKVFQQHYTNKIRALRNRLIV LLLECKRSRK |
| Quality Control Test : |
12.5% SDS-PAGE Stained with Coomassie Blue. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
