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Recombinant Human C3 Protein, MYC/DDK-tagged

Cat.No. : C3-1841H
Product Overview : Recombinant human C3 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
  • Specification
  • Gene Information
  • Related Products
Description : C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [UniProtKB/Swiss-Prot Function]
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 187 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : C3 complement component 3 [ Homo sapiens ]
Official Symbol : C3
Synonyms : AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p
Gene ID : 718
mRNA Refseq : NM_000064
Protein Refseq : NP_000055
MIM : 120700
UniProt ID : P01024

Products Types

◆ Recombinant Protein
C3-732M Recombinant Mouse C3 Protein, MYC/DDK-tagged +Inquiry
C3-1149H Recombinant Human C3 Protein, His-tagged +Inquiry
C3-2505H Recombinant Human C3 protein(961-1040 aa), C-His-tagged +Inquiry
C3-471H Recombinant Human C3 Protein, His (Fc)-Avi-tagged +Inquiry
C3-7632M Recombinant Mouse C3 protein, His-tagged +Inquiry

See All C3 Recombinant Protein

◆ Native Protein
C3-05M Native Mouse C3 Protein +Inquiry
C3-08R Native Rat C3 Protein +Inquiry
C3-8391H Native Human C3 +Inquiry

See All C3 Native Protein

Related Gene

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Have proteins been found to interact with C3 proteins? 10/26/2019

Yes, a variety of proteins that interact with C3 proteins, including complement receptors, regulatory proteins, inflammatory factors, etc., have been discovered, and they are jointly involved in the regulation and functional execution of C3 proteins.

What is the relationship between C3 protein and infectious diseases? 09/28/2019

C3 protein plays an important role in infectious diseases. It can play an anti-infection role by activating the complement system, directly killing pathogens or enhancing the ability of immune cells to destroy pathogens.

How is the research progress of C3 protein at present? 09/23/2019

Research on C3 protein is going on. At present, it mainly focuses on the analysis of its function and regulatory mechanism, the identification of gene mutations associated with diseases, and the interaction with other complement proteins and immune cells, which provides a theoretical basis for the further development of diagnosis and treatment methods of related diseases.

What is the use of C3 protein in laboratory diagnostics? 05/24/2019

C3 protein can be used as an aid in the diagnosis of certain immune-related diseases. Measuring the level of C3 protein in serum can reflect the activity of the immune system and the degree of inflammation.

What are the effects of post-translational modifications of C3 protein on its function? 04/15/2019

Post-translational modifications of the C3 protein can affect its function. Phosphorylation, cleavage, methylation and other modifications can regulate the activity, stability and interaction ability of C3 proteins.

Have any drug treatments associated with C3 protein been identified? 02/22/2019

Yes, some C3 protein-related drug treatments are under development, including drugs that regulate the degree of C3 protein activation, drugs that inhibit the overactivation of C3 protein, etc.

Customer Reviews (3)

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Reviews
02/23/2022

    Expression efficiency is high. In our experiments, we found that the target protein can be synthesized quickly and effectively.

    01/26/2022

      Activity was not significantly different from the native protein, as expected.

      03/23/2021

        High purity, no obvious impurities.

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