Recombinant Human C3 Protein, MYC/DDK-tagged
Cat.No. : | C3-1841H |
Product Overview : | Recombinant human C3 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293 |
- Specification
- Gene Information
- Related Products
Description : | C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [UniProtKB/Swiss-Prot Function] |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 187 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | C3 complement component 3 [ Homo sapiens ] |
Official Symbol : | C3 |
Synonyms : | AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p |
Gene ID : | 718 |
mRNA Refseq : | NM_000064 |
Protein Refseq : | NP_000055 |
MIM : | 120700 |
UniProt ID : | P01024 |
Products Types
◆ Recombinant Protein | ||
C3-732M | Recombinant Mouse C3 Protein, MYC/DDK-tagged | +Inquiry |
C3-1149H | Recombinant Human C3 Protein, His-tagged | +Inquiry |
C3-2505H | Recombinant Human C3 protein(961-1040 aa), C-His-tagged | +Inquiry |
C3-471H | Recombinant Human C3 Protein, His (Fc)-Avi-tagged | +Inquiry |
C3-7632M | Recombinant Mouse C3 protein, His-tagged | +Inquiry |
◆ Native Protein | ||
C3-05M | Native Mouse C3 Protein | +Inquiry |
C3-08R | Native Rat C3 Protein | +Inquiry |
C3-8391H | Native Human C3 | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionYes, a variety of proteins that interact with C3 proteins, including complement receptors, regulatory proteins, inflammatory factors, etc., have been discovered, and they are jointly involved in the regulation and functional execution of C3 proteins.
C3 protein plays an important role in infectious diseases. It can play an anti-infection role by activating the complement system, directly killing pathogens or enhancing the ability of immune cells to destroy pathogens.
Research on C3 protein is going on. At present, it mainly focuses on the analysis of its function and regulatory mechanism, the identification of gene mutations associated with diseases, and the interaction with other complement proteins and immune cells, which provides a theoretical basis for the further development of diagnosis and treatment methods of related diseases.
C3 protein can be used as an aid in the diagnosis of certain immune-related diseases. Measuring the level of C3 protein in serum can reflect the activity of the immune system and the degree of inflammation.
Post-translational modifications of the C3 protein can affect its function. Phosphorylation, cleavage, methylation and other modifications can regulate the activity, stability and interaction ability of C3 proteins.
Yes, some C3 protein-related drug treatments are under development, including drugs that regulate the degree of C3 protein activation, drugs that inhibit the overactivation of C3 protein, etc.
Customer Reviews (3)
Write a reviewExpression efficiency is high. In our experiments, we found that the target protein can be synthesized quickly and effectively.
Activity was not significantly different from the native protein, as expected.
High purity, no obvious impurities.
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