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Recombinant Human CADM1 Protein, MYC/DDK-tagged

Cat.No. : CADM1-2260H
Product Overview : Recombinant human CADM1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 48.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : CADM1 cell adhesion molecule 1 [ Homo sapiens ]
Official Symbol : CADM1
Synonyms : BL2; IGSF4; IGSF4A; Necl-2; NECL2; RA175; sgIGSF; ST17; sTSLC-1; SYNCAM; synCAM1; TSLC1
Gene ID : 23705
mRNA Refseq : NM_001098517
Protein Refseq : NP_001091987
MIM : 605686
UniProt ID : Q9BY67

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How do genetic variations or mutations in the CADM1 gene affect its function, and what are the medical implications of these variations in diseases such as autism spectrum disorders and cancer? 01/31/2022

Mutations or genetic variations in CADM1 can lead to altered protein function, potentially contributing to the development of diseases like autism spectrum disorders and various cancers. Studying these variations helps uncover their specific roles in disease progression.

What is the role of CADM1 in cell adhesion, and how does it contribute to cellular processes in various tissues? 10/01/2021

CADM1 is a cell adhesion molecule that plays a crucial role in maintaining tissue integrity and mediating cell-cell adhesion. It is involved in various cellular processes, including tissue development, immune response, and neural cell connectivity.

Can you discuss the post-translational modifications of CADM1 and their relevance in cell signaling pathways and disease contexts? 05/08/2021

Post-translational modifications of CADM1, such as phosphorylation and glycosylation, play critical roles in modulating its interactions and functions. Understanding these modifications is important for unraveling disease mechanisms and potential therapeutic targets.

How does CADM1 contribute to the regulation of immune responses, particularly in the context of autoimmune diseases and immune cell interactions? 10/10/2019

CADM1 mediates immune cell interactions and regulates immune responses. Dysregulation of CADM1 has been implicated in autoimmune diseases like multiple sclerosis, where it affects immune cell adhesion and migration.

What are the current therapeutic approaches targeting CADM1 in cancer treatment, and what challenges exist in developing CADM1-specific therapies for clinical use? 02/14/2018

Therapeutic strategies targeting CADM1 in cancer treatment include antibody-based therapies and small molecule inhibitors. Challenges include ensuring specificity and minimizing potential side effects, given the diverse roles of CADM1 in different tissues.

Customer Reviews (3)

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Reviews
06/09/2021

    Good quality - it's an essential part of our research.

    05/17/2019

      I highly recommend this product!

      06/09/2018

        Friendly services!

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