Recombinant Human CADM1 Protein, MYC/DDK-tagged
Cat.No. : | CADM1-2260H |
Product Overview : | Recombinant human CADM1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293 |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 48.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | CADM1 cell adhesion molecule 1 [ Homo sapiens ] |
Official Symbol : | CADM1 |
Synonyms : | BL2; IGSF4; IGSF4A; Necl-2; NECL2; RA175; sgIGSF; ST17; sTSLC-1; SYNCAM; synCAM1; TSLC1 |
Gene ID : | 23705 |
mRNA Refseq : | NM_001098517 |
Protein Refseq : | NP_001091987 |
MIM : | 605686 |
UniProt ID : | Q9BY67 |
Products Types
◆ Recombinant Protein | ||
Cadm1-1180M | Recombinant Mouse Cadm1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cadm1-1931M | Recombinant Mouse Cadm1 Protein, Myc/DDK-tagged | +Inquiry |
CADM1-112H | Recombinant Human CADM1 Protein, His-tagged | +Inquiry |
CADM1-428H | Recombinant Human CADM1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
CADM1-1182M | Recombinant Mouse CADM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CADM1-2527HCL | Recombinant Human CADM1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMutations or genetic variations in CADM1 can lead to altered protein function, potentially contributing to the development of diseases like autism spectrum disorders and various cancers. Studying these variations helps uncover their specific roles in disease progression.
CADM1 is a cell adhesion molecule that plays a crucial role in maintaining tissue integrity and mediating cell-cell adhesion. It is involved in various cellular processes, including tissue development, immune response, and neural cell connectivity.
Post-translational modifications of CADM1, such as phosphorylation and glycosylation, play critical roles in modulating its interactions and functions. Understanding these modifications is important for unraveling disease mechanisms and potential therapeutic targets.
CADM1 mediates immune cell interactions and regulates immune responses. Dysregulation of CADM1 has been implicated in autoimmune diseases like multiple sclerosis, where it affects immune cell adhesion and migration.
Therapeutic strategies targeting CADM1 in cancer treatment include antibody-based therapies and small molecule inhibitors. Challenges include ensuring specificity and minimizing potential side effects, given the diverse roles of CADM1 in different tissues.
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