Recombinant Human CCR2 Protein

• Cat.No.: CCR2-135H
• Product Overview: Recombinant Human CCR2 was expressed in Wheat Germ. Liposomes.

Specification

• Description: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
• Source: Wheat Germ
• Species: Human
• Form: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
• Molecular Mass: 41.2 kDa
• AA Sequence: MLSTSRSRFIRNTNESGEEVTTFFD YDYGAPCHKFDVKQIGAQLLPPLYS LVFIFGFVGNMLVVLILINCKKLKC LTDIYLLNLAISDLLFLITLPLWAH SAANEWVFGNAMCKLFTGLYHIGYF GGIFFIILLTIDRYLAIVHAVFALK ARTVTFGVVTSVITWLVAVFASVPG IIFTKCQKEDSVYVCGPYFPRGWNN FHTIMRNILGLVLPLLIMVICYSGI LKTLLRCRNEKKRHRAVRVIFTIMI VYFLFWTPYNIVILLNTFQEFFGLS NCESTSQLDQATQVTETLGMTHCCI NPIIYAFVGEKFRSLFHIALGCRIA PLQKPVCGGPGVRPGKNVKVTTQGL LDGRGKGKSIGRAPEASLQDKEGA
• Applications: Antibody Production; Functional Study; Compound Screening
• Notes: Best use within three months from the date of receipt of this protein. Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: CCR2 C-C motif chemokine receptor 2 [ Homo sapiens ]
• Official Symbol: CCR2
• Synonyms: CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2; MCP-1 receptor; chemokine (C-C motif) receptor 2; monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor
• Gene ID: 729230
• mRNA Refseq: NM_001123041
• Protein Refseq: NP_001116513
• MIM: 601267
• UniProt ID: P41597