Recombinant Human CCR6 Protein

• Cat.No.: CCR6-0695H
• Product Overview: Human CCR6 full-length ORF (NP_004358.2) recombinant protein without tag.

Specification

• Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 42.5 kDa
• AA Sequence: MSGESMNFSDVFDSSEDYFVSVNTS YYSVDSEMLLCSLQEVRQFSRLFVP IAYSLICVFGLLGNILVVITFAFYK KARSMTDVYLLNMAIADILFVLTLP FWAVSHATGAWVFSNATCKLLKGIY AINFNCGMLLLTCISMDRYIAIVQA TKSFRLRSRTLPRSKIICLVVWGLS VIISSSTFVFNQKYNTQGSDVCEPK YQTVSEPIRWKLLMLGLELLFGFFI PLMFMIFCYTFIVKTLVQAQNSKRH KAIRVIIAVVLVFLACQIPHNMVLL VTAANLGKMNRSCQSEKLIGYTKTV TEVLAFLHCCLNPVLYAFIGQKFRN YFLKILKDLWCVRRKYKSSGFSCAG RYSENISRQTSETADNDNASSFTM
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: CCR6 chemokine (C-C motif) receptor 6 [ Homo sapiens ]
• Official Symbol: CCR6
• Synonyms: CCR6; chemokine (C-C motif) receptor 6; STRL22; C-C chemokine receptor type 6; BN 1; CD196; CKR L3; CMKBR6; DCR2; DRY 6; GPR CY4; GPR29; LARC receptor; chemokine receptor-like 3; chemokine (C-C) receptor 6; G protein-coupled receptor 29; G-protein coupled receptor 29; seven-transmembrane receptor, lymphocyte, 22; BN-1; DRY6; CCR-6; CKRL3; CKR-L3; GPRCY4; CC-CKR-6; C-C CKR-6
• Gene ID: 1235
• mRNA Refseq: NM_004367
• Protein Refseq: NP_004358
• MIM: 601835
• UniProt ID: P51684