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Recombinant Human CCR7 Protein, MYC/DDK-tagged

Cat.No. : CCR7-3045H
Product Overview : Recombinant Human CCR7 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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  • Gene Information
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Description : Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 40.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : CCR7 chemokine (C-C motif) receptor 7 [ Homo sapiens ]
Official Symbol : CCR7
Synonyms : BLR2; CD197; CDw197; CMKBR7; EBI1
Gene ID : 1236
mRNA Refseq : NM_001838
Protein Refseq : NP_001829
MIM : 600242
UniProt ID : P32248

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does CCR7 contribute to lymphocyte trafficking and homing? 01/23/2022

It directs T cells and dendritic cells to lymph nodes, ensuring proper immune surveillance.

What therapeutic strategies are being explored targeting CCR7 for disease treatment? 12/24/2021

Therapeutic strategies include targeting CCR7 to modulate immune responses in autoimmune diseases and cancer.

How is CCR7 implicated in cancer progression and metastasis? 07/08/2021

CCR7 can facilitate tumor cell invasion and metastasis to lymph nodes.

What role does CCR7 play in the formation of immune synapses? 03/15/2021

CCR7 helps form immune synapses for effective T cell activation.

What is the main function of CCR7 in the immune system? 03/01/2021

CCR7 guides the migration of various immune cells to lymphoid tissues, aiding in immune responses.

In which cells or tissues is CCR7 predominantly expressed? 06/27/2020

CCR7 is predominantly expressed in T cells, dendritic cells, and various other immune cells.

Are there known genetic mutations or alterations in CCR7 associated with specific diseases? 07/14/2019

Genetic alterations in CCR7 have been linked to certain autoimmune diseases and cancers.

Customer Reviews (3)

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Reviews
10/16/2022

    Perfect for protein research.

    04/05/2022

      Fast delivery, outstanding product.

      03/14/2022

        Product works as intended.

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