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Recombinant Human CD160 Protein, GST-Tagged

Cat.No. : CD160-0724H
Product Overview : Human CD160 full-length ORF (NP_008984.1, 1 a.a. - 181 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
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Description : CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 46.2 kDa
AA Sequence : MLLEPGRGCCALAILLAIVDIQSGG CINITSSASQEGTRLNLICTVWHKK EEAEGFVVFLCKDRSGDCSPETSLK QLRLKRDPGIDGVGEISSQLMFTIS QVTPLHSGTYQCCARSQKSGIRLQG HFFSILFTETGNYTVTGLKQRQHLE FSHNEGTLSSGFLQEKVWVMLVTSL VALQAL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CD160 CD160 molecule [ Homo sapiens ]
Official Symbol : CD160
Synonyms : CD160; CD160 molecule; CD160 antigen; BY55; NK1; NK28; CD160-delta Ig; CD160 transmembrane isoform; natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member; FLJ46513;
Gene ID : 11126
mRNA Refseq : NM_007053
Protein Refseq : NP_008984
MIM : 604463
UniProt ID : O95971

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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