Recombinant Human CD40LG Protein, His-Flag-StrepII-Tagged

• Cat.No.: CD40LG-0816H
• Product Overview: Purified CD40LG (AAH74950.1, 116 a.a. - 261 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.

Specification

• Description: The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]
• Source: Human cells
• Species: Human
• Tag: His-Flag-StrepII
• Form: Liquid
• Bio-activity: Not Tested
• Molecular Mass: 21.34 kDa
• AA Sequence: GDQNPQIAAHVISEASSKTTSVLQW AEKGYYTMSNNLVTLENGKQLTVKR QGLYYIYAQVTFCSNREASSQAPFI ASLCLKSPGRFERILLRAANTHSSA KPCGQQSIHLGGVFELQPGASVFVN VTDPSQVSHGTGFTSFGLLKL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: ≥ 10 μg/mL
• Storage Buffer: 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.

Gene Information

• Gene Name: CD40LG CD40 ligand [ Homo sapiens ]
• Official Symbol: CD40LG
• Synonyms: CD40LG; CD40 ligand; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; tumor necrosis factor (ligand) superfamily member 5; CD40-L; T-cell antigen Gp39; T-B cell-activating molecule; TNF-related activation protein; IGM; IMD3; HIGM1; T-BAM; TNFSF5
• Gene ID: 959
• mRNA Refseq: NM_000074
• Protein Refseq: NP_000065
• MIM: 300386
• UniProt ID: P29965