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Recombinant Human CD40LG protein, His & GST-tagged

Cat.No. : CD40LG-785H
Product Overview : Recombinant Human CD40LG aa. (Met1~Leu261 (Accession # P29965)) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Human
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 61.7kDa
Protein length : Met1~Leu261 (Accession # P29965)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.5.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH 7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : CD40LG CD40 ligand [ Homo sapiens (human) ]
Official Symbol : CD40LG
Synonyms : IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L; CD40 antigen ligand; CD40-L; T-B cell-activating molecule; T-cell antigen Gp39; TNF-related activation protein; tumor necrosis factor (ligand) superfamily member 5; CD40 ligand
Gene ID : 959
mRNA Refseq : NM_000074.2
Protein Refseq : NP_000065.1
UniProt ID : P29965

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any ongoing clinical trials targeting CD40LG for autoimmune diseases? 11/01/2022

Yes, there are clinical trials investigating the modulation of CD40LG in autoimmune diseases, exploring its potential role in regulating immune responses that contribute to autoimmunity.

Can CD40LG be a potential target for the treatment of infectious diseases? 02/27/2021

Yes, research suggests that CD40LG modulation might be a viable strategy in the development of treatments for infectious diseases by enhancing immune responses.

How does the interaction between CD40LG and its receptor CD40 influence antibody production? 11/20/2020

The interaction between CD40LG and CD40 is crucial for the activation of B cells, leading to the production of antibodies and the development of an effective immune response.

How is CD40LG involved in the regulation of inflammatory responses? 08/26/2020

CD40LG is involved in modulating inflammatory responses by influencing the activation and function of immune cells, contributing to the regulation of the immune system.

In what ways is CD40LG being explored for its potential in vaccine development? 04/20/2020

CD40LG is being investigated as an adjuvant in vaccine development, aiming to enhance the immune response and improve the efficacy of vaccines against various diseases.

Customer Reviews (3)

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Reviews
10/17/2022

    The reliable performance of the CD40LG protein in ELISA and its compatibility with protein electron microscopy structure analysis make it an excellent choice for a wide range of research studies.

    01/01/2022

      Its reliable and accurate performance ensures dependable results, contributing to the advancement of scientific knowledge in various fields of study.

      11/16/2020

        Their knowledgeable and responsive team assists in troubleshooting and finding solutions to any experimental challenges that may arise.

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