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Recombinant Human CD63 Protein, MYC/DDK-tagged

Cat.No. : CD63-3112H
Product Overview : Recombinant Human CD63 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 25.2 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : CD63 CD63 molecule [ Homo sapiens ]
Official Symbol : CD63
Synonyms : LAMP-3; ME491; MLA1; OMA81H; TSPAN30
Gene ID : 967
mRNA Refseq : NM_001257389
Protein Refseq : NP_001244318
MIM : 155740
UniProt ID : P08962

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How is CD63 involved in cancer progression? 08/12/2022

It is associated with cancer progression, impacting cell migration and metastasis.

What role does CD63 play in immune cell function? 01/27/2021

CD63 modulates immune responses, influencing antigen presentation and cell activation.

Are there potential therapeutic applications targeting CD63? 10/03/2020

Targeting CD63 may offer therapeutic potential in cancer and immune-related diseases.

How is CD63 expression regulated in cells? 05/12/2020

Its expression is regulated through transcriptional and post-translational mechanisms.

How does CD63 contribute to vesicular trafficking? 01/02/2019

It helps in the sorting and transport of proteins within endosomes and lysosomes.

What is the relationship between CD63 and exosomes? 08/07/2018

CD63 is a marker for exosomes, playing a role in their formation and function.

What is the primary function of CD63 in cellular processes? 01/18/2018

CD63 is involved in vesicular trafficking, cell adhesion, and signaling.

Customer Reviews (3)

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Reviews
11/26/2022

    Consistent and reliable protein.

    08/23/2022

      Excellent yield, very pure.

      06/19/2021

        Perfect for specific experiments.

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