Recombinant Human CD68 Protein

• Cat.No.: CD68-0841H
• Product Overview: Human CD68 full-length ORF (NP_001242.2) recombinant protein without tag.

Specification

• Description: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 37.4 kDa
• AA Sequence: MRLAVLFSGALLGLLAAQGTGNDCP HKKSATLLPSFTVTPTVTESTGTTS HRTTKSHKTTTHRTTTTGTTSHGPT TATHNPTTTSHGNVTVHPTSNSTAT SQGPSTATHSPATTSHGNATVHPTS NSTATSPGFTSSAHPEPPPPSPSPS PTSKETIGDYTWTNGSQPCVHLQAQ IQIRVMYTTQGGGEAWGISVLNPNK TKVQGSCEGAHPHLLLSFPYGHLSF GFMQDLQQKVVYLSYMAVEYNVSFP HAAQWTFSAQNASLRDLQAPLGQSF SCSNSSIILSPAVHLDLLSLRLQAA QLPHTGVFGQSFSCPSDRSILLPLI IGLILLGLLALVLIAFCIIRRRPSA YQAL
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: CD68 CD68 molecule [ Homo sapiens ]
• Official Symbol: CD68
• Synonyms: CD68; CD68 molecule; CD68 antigen; macrosialin; DKFZp686M18236; GP110; LAMP4; macrophage antigen CD68; SCARD1; scavenger receptor class D; member 1; scavenger receptor class D, member 1
• Gene ID: 968
• mRNA Refseq: NM_001040059
• Protein Refseq: NP_001035148
• MIM: 153634
• UniProt ID: P34810