Recombinant Human CD86 Protein, His-Flag-StrepII-Tagged
| Cat.No. : | CD86-0873H |
| Product Overview : | Purified CD86 (AAH40261.1, 24 a.a. - 246 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells. |
- Specification
- Gene Information
- Related Products
| Description : | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] |
| Source : | Human cells |
| Species : | Human |
| Tag : | His-Flag-StrepII |
| Form : | Liquid |
| Bio-activity : | Not Tested |
| Molecular Mass : | 29.81 kDa |
| AA Sequence : | APLKIQAYFNETADLPCQFANSQNQ SLSELVVFWQDQENLVLNEVYLGKE KFDSVHSKYMGRTSFDSDSWTLRLH NLQIKDKGLYQCIIHHKKPTGMIRI HQMNSELSVLANFSQPEIVPISNIT ENVYINLTCSSIHGYPEPKKMSVLL RTKNSTIEYDGIMQKSQDNVTELYD VSISLSVSFPDVTSNMTIFCILETD KTRLLSSPFSIELEDPQPPPDHI |
| Applications : | Western Blot Enzyme-linked Immunoabsorbent Assay SDS-PAGE Protein Interaction |
| Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Concentration : | ≥ 10 μg/mL |
| Storage Buffer : | 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin. |
| Gene Name : | CD86 CD86 molecule [ Homo sapiens ] |
| Official Symbol : | CD86 |
| Synonyms : | CD86; CD86 molecule; CD28LG2, CD86 antigen (CD28 antigen ligand 2, B7 2 antigen); T-lymphocyte activation antigen CD86; B lymphocyte antigen B7 2; B7 2; B7.2; BU63; FUN-1; CTLA-4 counter-receptor B7.2; B-lymphocyte activation antigen B7-2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); B70; B7-2; LAB72; CD28LG2; MGC34413; |
| Gene ID : | 942 |
| mRNA Refseq : | NM_001206924 |
| Protein Refseq : | NP_001193853 |
| MIM : | 601020 |
| UniProt ID : | P42081 |
Products Types
| ◆ Lysates | ||
| CD86-1013CCL | Recombinant Cynomolgus CD86 cell lysate | +Inquiry |
| CD86-1971RCL | Recombinant Rat CD86 cell lysate | +Inquiry |
| CD86-2598MCL | Recombinant Mouse CD86 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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