Recombinant Human CD86 protein, His & T7-tagged
Cat.No. : | CD86-7780H |
Product Overview : | Recombinant Human CD86 aa. (Gln46~Cys282 (Accession # P42081)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
Source : | E. coli |
Species : | Human |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 30.9kDa |
Protein length : | Gln46~Cys282 (Accession # P42081) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 8.2. |
Applications : | SDS-PAGE; WB; ELISA; IP |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4 |
Gene Name : | CD86 CD86 molecule [ Homo sapiens (human) ] |
Official Symbol : | CD86 |
Synonyms : | CD86; CD86 molecule; B70; B7-2; B7.2; LAB72; CD28LG2; T-lymphocyte activation antigen CD86; B-lymphocyte activation antigen B7-2; BU63; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CTLA-4 counter-receptor B7.2; FUN-1 |
Gene ID : | 942 |
mRNA Refseq : | NM_001206924.1 |
Protein Refseq : | NP_001193853.1 |
UniProt ID : | P42081 |
Products Types
◆ Recombinant Protein | ||
CD86-595H | Recombinant Human CD86 Protein, Fc-tagged | +Inquiry |
Cd86-703M | Recombinant Mouse Cd86 Protein, His-tagged | +Inquiry |
CD86-176H | Recombinant Human CD86 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD86-704H | Recombinant Human CD86 Protein, His-tagged | +Inquiry |
CD86-592C | Recombinant Cynomolgus monkey CD86 Protein | +Inquiry |
◆ Lysates | ||
CD86-2619HCL | Recombinant Human CD86 cell lysate | +Inquiry |
CD86-2598MCL | Recombinant Mouse CD86 cell lysate | +Inquiry |
CD86-1971RCL | Recombinant Rat CD86 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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