Recombinant Human CD8B Protein, Fc-tagged

• Cat.No.: CD8B-270H
• Product Overview: Recombinant human CD8B isoform 1 (P10966-1) extracellular domain (Met 1-Pro 170) was fused with the Fc region of human IgG1 at the C-terminus.

Specification

• Source: HEK293
• Species: Human
• Tag: Fc
• Predicted N Terminal: Leu 22
• Form: Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
• Molecular Mass: The recombinant human CD8B/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 390 amino acids and has a predicted molecular mass of 44 kDa. The apparent molecular mass of the reduced monomer is approximately 50 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >93 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CD8B CD8b molecule [ Homo sapiens ]
• Official Symbol: CD8B
• Synonyms: CD8B; CD8b molecule; CD8 antigen, beta polypeptide 1 (p37) , CD8B1; T-cell surface glycoprotein CD8 beta chain; CD8 antigen, beta polypeptide 1 (p37); T lymphocyte surface glycoprotein beta chain; LY3; P37; LEU2; LYT3; CD8B1; MGC119115
• Gene ID: 926
• mRNA Refseq: NM_001178100
• Protein Refseq: NP_001171571
• MIM: 186730
• UniProt ID: P10966
• Chromosome Location: 2p12
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Disease, organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem