Recombinant Human CDC37 Protein, GST-Tagged

• Cat.No.: CDC37-0930H
• Product Overview: Human CDC37 full-length ORF (AAH08793.1, 1 a.a. - 378 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 67.32 kDa
• AA Sequence: MMDYSVWDHIEVSDDEDETHPNIDT ASLFRWRHQARVERMEQFQKEKEEL DRGCRECKRKVAECQRKLKELEVAE GGKAELERLQAEAQQLRKEERSWEQ KLEEMRKKEKSMPWNVDTLSKDGFS KSMVNTKPEKTEEDSEEVREQKHKT FVEKYEKQIKHFGMLRRWDDSQKYL SDNVHLVCEETANYLVIWCIDLEVE EKCALMEQVAHQTIVMQFILELAKS LKVDPRACFRQFFTKIKIADRQYME GFNDELEAFKERVRGRAKLRIEKAM KEYEEEERKKRLGPGGLDPVEVYES LPEELQKCFDVKDVQMLQDAISKMD PTDAKYHVQRCIDSGLWVPNSKASE AKEGEEAGPGDPLLEAVPKTGDEKD VSV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CDC37 cell division cycle 37 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: CDC37
• Synonyms: CDC37; cell division cycle 37 homolog (S. cerevisiae); CDC37 (cell division cycle 37, S. cerevisiae, homolog), CDC37 cell division cycle 37 homolog (S. cerevisiae); hsp90 co-chaperone Cdc37; CDC37 (cell division cycle 37; S. cerevisiae; homolog); CDC37 cell division cycle 37 homolog; Hsp90 co chaperone Cdc37; P50CDC37; hsp90 chaperone protein kinase-targeting subunit; CDC37 (cell division cycle 37, S. cerevisiae, homolog)
• Gene ID: 11140
• mRNA Refseq: NM_007065
• Protein Refseq: NP_008996
• MIM: 605065
• UniProt ID: Q16543