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Recombinant Human CDH12 Protein, GST-Tagged

Cat.No. : CDH12-0973H
Product Overview : Human CDH12 full-length ORF (NP_004052.2, 1 a.a. - 794 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 114.7 kDa
AA Sequence : MLTRNCLSLLLWVLFDGGLLTPLQP QPQQTLATEPRENVIHLPGQRSHFQ RVKRGWVWNQFFVLEEYVGSEPQYV GKLHSDLDKGEGTVKYTLSGDGAGT VFTIDETTGDIHAIRSLDREEKPFY TLRAQAVDIETRKPLEPESEFIIKV QDINDNEPKFLDGPYVATVPEMSPV GAYVLQVKATDADDPTYGNSARVVY SILQGQPYFSIDPKTGVIRTALPNM DREVKEQYQVLIQAKDMGGQLGGLA GTTIVNITLTDVNDNPPRFPKSIFH LKVPESSPIGSAIGRIRAVDPDFGQ NAEIEYNIVPGDGGNLFDIVTDEDT QEGVIKLKKPLDFETKKAYTFKVEA SNLHLDHRFHSAGPFKDTATVKISV LDVDEPPVFSKPLYTMEVYEDTPVG TIIGAVTAQDLDVGSSAVRYFIDWK SDGDSYFTIDGNEGTIATNELLDRE STAQYNFSIIASKVSNPLLTSKVNI LINVLDVNEFPPEISVPYETAVCEN AKPGQIIQIVSAADRDLSPAGQQFS FRLSPEAAIKPNFTVRDFRNNTAGI ETRRNGYSRRQQELYFLPVVIEDSS YPVQSSTNTMTIRVCRCDSDGTILS CNVEAIFLPVGLSTGALIAILLCIV ILLAIVVLYVALRRQKKKDTLMTSK EDIRDNVIHYDDEGGGEEDTQAFDI GALRNPKVIEENKIRRDIKPDSLCL PRQRPPMEDNTDIRDFIHQRLQEND VDPTAPPYDSLATYAYEGSGSVAES LSSIDSLTTEADQDYDYLTDWGPRF KVLADMFGEEESYNPDKVT
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CDH12 cadherin 12, type 2 (N-cadherin 2) [ Homo sapiens ]
Official Symbol : CDH12
Synonyms : CDH12; cadherin 12, type 2 (N-cadherin 2); cadherin-12; Br cadherin; CDHB; Br-cadherin; N-cadherin 2; brain cadherin; brain-cadherin; neuronal cadherin 2; neural type cadherin 2; cadherin, neural type, 2; FLJ34857;
Gene ID : 1010
mRNA Refseq : NM_004061
Protein Refseq : NP_004052
MIM : 600562
UniProt ID : P55289

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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