| Description : |
This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. |
| Source : |
HEK293 cells |
| Tag : |
Fc |
| Form : |
Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4. |
| Molecular Mass : |
93.5kD |
| AA Sequence : |
TLSTPLSKRTSGFPAKKRALELSGN SKNELNRSKRSWMWNQFFLLEEYTG SDYQYVGKLHSDQDRGDGSLKYILS GDGAGDLFIINENTGDIQATKRLDR EEKPVYILRAQAINRRTGRPVEPES EFIIKIHDINDNEPIFTKEVYTATV PEMSDVGTFVVQVTATDADDPTYGN SAKVVYSILQGQPYFSVESETGIIK TALLNMDRENREQYQVVIQAKDMGG QMGGLSGTTTVNITLTDVNDNPPRF PQSTYQFKTPESSPPGTPIGRIKAS DADVGENAEIEYSITDGEGLDMFDV ITDQETQEGIITVKKLLDFEKKKVY TLKVEASNPYVEPRFLYLGPFKDSA TVRIVVEDVDEPPVFSKLAYILQIR EDAQINTTIGSVTAQDPDAARNPVK YSVDRHTDMDRIFNIDSGNGSIFTS KLLDRETLLWHNITVIATEINNPKQ SSRVPLYIKVLDVNDNAPEFAEFYE TFVCEKAKADQLIQTLHAVDKDDPY SGHQFSFSLAPEAASGSNFTIQDNK DNTAGILTRKNGYNRHEMSTYLLPV VISDNDYPVQSSTGTVTVRVCACDH HGNMQSCHAEALIHPTGLSTGAVDD IEGRMDEPKSCDKTHTCPPCPAPEL LGGPSVFLFPPKPKDTLMISRTPEV TCVVVDVSHEDPEVKFNWYVDGVEV HNAKTKPREEQYNSTYRVVSVLTVL HQDWLNGKEYKCKVSNKALPAPIEK TISKAKGQPREPQVYTLPPSREEMT KNQVSLTCLVKGFYPSDIAVEWESN GQPENNYKTTPPVLDSDGSFFLYSK LTVDKSRWQQGNVFSCSVMHEALHN HYTQKSLSLSPGK |
| Endotoxin : |
< 0.1 EU per µg protein as determined by LAL test |
| Purity : |
>95% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : |
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
