Active Recombinant Human CDK7/CCNH protein, His-tagged
| Cat.No. : | CDK7-CCNH-313H |
| Product Overview : | Recombinant full-length human CDK7 and CCNH were co-expressed by baculovirus in Sf9 insect cells using an N-terminal His tags. |
- Specification
- Gene Information
- Related Products
| Description : | CDK7 gene is a member of the cyclin-dependent protein kinase family that is important regulators of cell cycle progression. CDK7 forms a trimeric complex with cyclin H and MAT1, which functions as a CDK-activating kinase (CAK). CDK7 is an essential component of the transcription factor TFIIH that is involved in transcription initiation and DNA repair. CDK7 is thought to serve as a direct link between the regulation of transcription and the cell cycle. |
| Source : | Insect cell |
| Species : | Human |
| Tag : | His |
| Form : | 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol |
| Bio-activity : | The specific activity of CDK7/CyclinH1 was determined to be 56nmol/min/mg as per activity protocol. |
| Molecular Mass : | CDK7 ~41~43 kDa, and CCNH ~39 kDa |
| Purity : | The purity of CDK7/CCNH was determined to be >70% by densitometry. |
| Applications : | Kinase Assay; WB |
| Stability : | 1 year at -70 centigrade |
| Storage : | Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Concentration : | 0.1 μg/μL |
| Gene Name : | cyclin dependent kinase 7 [ Homo sapiens (human) ]; cyclin H [ Homo sapiens (human) ] |
| Official Symbol : | CDK7; CCNH |
| Synonyms : | CAK; CAK1; HCAK; MO15; STK1; CDKN7; P39mo15; Cyclin H1; CCNH; CAK; p34; p37 |
| Gene ID : | 1022; 902 |
| mRNA Refseq : | NM_001799; NM_001239 |
| Protein Refseq : | NP_001790.1; NP_001230.1 |
| MIM : | 601955; 601953 |
| UniProt ID : | P50613; P51946 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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