Recombinant Human CEACAM5 Protein, GST-Tagged

• Cat.No.: CEACAM5-1095H
• Product Overview: Human CEACAM5 full-length ORF (AAH34671.1, 1 a.a. - 702 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 103.2 kDa
• AA Sequence: MESPSAPPHRWCIPWQRLLLTASLL TFWNPPTTAKLTIESTPFNVAEGKE VLLLVHNLPQHLFGYSWYKGERVDG NRQIIGYVIGTQQATPGPAYSGREI IYPNASLLIQNIIQNDTGFYTLHVI KSDLVNEEATGQFRVYPELPKPSIS SNNSKPVEDKDAVAFTCEPETQDAT YLWWVNNQSLPVSPRLQLSNGNRTL TLFNVTRNDSASYKCETQNPVSARR SDSVILNVLYGPDAPTISPLNTSYR SGENLNLSCHAASNPPAQYSWFVNG TFQQSTQELFIPNITVNNSGSYTCQ AHNSDTGLNRTTVTTITVYAEPPKP FITSNNSNPVEDEDAVALTCEPEIQ NTTYLWWVNNQSLPVSPRLQLSNDN RTLTLLSVTRNDVGPYECGIQNELS VDHSDPVILNVLYGPDDPTISPSYT YYRPGVNLSLSCHAASNPPAQYSWL IDGNIQQHTQELFISNITEKNSGLY TCQANNSASGHSRTTVKTITVSAEL PKPSISSNNSKPVEDKDAVAFTCEP EAQNTTYLWWVNGQSLPVSPRLQLS NGNRTLTLFNVTRNDARAYVCGIQN SVSANRSDPVTLDVLYGPDTPIISP PDSSYLSGANLNLSCHSASNPSPQY SWRINGIPQQHTQVLFIAKITPNNN GTYACFVSNLATGRNNSIVKSITVS ASGTSPGLSAGATVGIMIGVLVGVA LI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 [ Homo sapiens ]
• Official Symbol: CEACAM5
• Synonyms: CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100; DKFZp781M2392
• Gene ID: 1048
• mRNA Refseq: NM_004363
• Protein Refseq: NP_004354
• MIM: 114890
• UniProt ID: P06731