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Recombinant Human CEACAM6 Protein, GST-Tagged

Cat.No. : CEACAM6-1096H
Product Overview : Human CEACAM6 full-length ORF (AAH05008.1, 1 a.a. - 344 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 63.47 kDa
AA Sequence : MGPPSAPPCRLHVPWKEVLLTASLL TFWNPPTTAKLTIESTPFNVAEGKE VLLLAHNLPQNRIGYSWYKGERVDG NSLIVGYVIGTQQATPGPAYSGRET IYPNASLLIQNVTQNDTGFYTLQVI KSDLVNEEATGQFHVYPELPKPSIS SNNSNPVEDKDAVAFTCEPEVQNTT YLWWVNGQSLPVSPRLQLSNGNMTL TLLSVKRNDAGSYECEIQNPASANR SDPVTLNVLYGPDVPTISPSKANYR PGENLNLSCHAASNPPAQYSWFING TFQQSTQELFIPNITVNNSGSYMCQ AHNSATGLNRTTVTMITVSGSAPVL SAVATVGITIGVLARVALI
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) [ Homo sapiens ]
Official Symbol : CEACAM6
Synonyms : CEACAM6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); NCA; carcinoembryonic antigen-related cell adhesion molecule 6; CD66c; normal cross-reacting antigen; non-specific crossreacting antigen; CEAL;
Gene ID : 4680
mRNA Refseq : NM_002483
Protein Refseq : NP_002474
MIM : 163980
UniProt ID : P40199

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does CEACAM6 contribute to inflammation? 04/19/2022

CEACAM6 is involved in regulating the inflammatory response in the gut, making it relevant to inflammatory bowel disease.

Are there diagnostic tests for CEACAM6 in inflammatory bowel disease? 09/01/2020

CEACAM6 levels can be measured in clinical tests to assess inflammation in the gastrointestinal tract.

Can CEACAM6 be used for monitoring disease progression? 10/10/2018

Yes, CEACAM6 levels can be monitored to track the progression of certain diseases.

Are there therapeutic strategies targeting CEACAM6 in infections? 12/16/2017

Research is ongoing to develop therapies that inhibit CEACAM6 interactions with pathogens to prevent infection.

Is CEACAM6 protein used in immunotherapy for cancer? 03/02/2016

Some immunotherapeutic approaches involve targeting CEACAM6 to enhance the immune response against cancer cells.

Customer Reviews (3)

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Reviews
05/23/2022

    They provide a wealth of technical information and extensive documentation about the CEACAM6 protein, ensuring I have a comprehensive understanding of its characteristics, handling protocols, and storage requirements.

    11/13/2021

      the manufacturer ensures a streamlined supply chain management system to meet my trial's requirements.

      11/16/2020

        the manufacturer facilitates access to the latest scientific advancements and developments related to CEACAM6 protein research.

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