Recombinant Human CFTR protein, GST-tagged
| Cat.No. : | CFTR-275H |
| Product Overview : | Recombinant Human CFTR fused with GST tag was expressed in E. coli. |
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- Specification
- Gene Information
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| Source : | E. coli |
| Species : | Human |
| Tag : | GST |
| Form : | 20 mM Tris-HCl, 0.15 M NaCl, pH 8.0 |
| AA Sequence : | MSPILGYWKIKGLVQPTRLLLEYLE EKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYI ADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSK LPE MLKMFEDRLCHKTYLNGDHVTHPDF MLYDALDVVLYMDPMCLDAFPKLVC FKKRIEAIPQIDKYLKSSKYIAWPL QGWQATFGGGDHPPKSDLVPRGSYQ IIRRTLKQAFADCTVILCEHRIEAM L ECQQFLVIEENKVRQYDSIQKLLNE RSLFRQAISPSDRVKLFPHRNSSKC KSKPQIAALKEETEEEVQDTRL |
| Storage : | For long term storage, prepare aliquots and store at -20 ~ -80 centigrade. Avoid freeze/thaw cycles. |
| Publication : |
Cystic Fibrosis Transmembrane Conductance Regulator Attaches Tumor Suppressor PTEN to the Membrane and Promotes Anti Pseudomonas aeruginosa Immunity (2017)
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| Gene Name : | CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) [ Homo sapiens ] |
| Official Symbol : | CFTR |
| Synonyms : | CFTR; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); ABCC7, CF, cystic fibrosis transmembrane conductance regulator, ATP binding cassette (sub family C, member 7); cystic fibrosis transmembrane conductance regulator; ABC35; ATP binding cassette sub family C; member 7; CFTR/MRP; dJ760C5.1; MRP7; TNR CFTR; cAMP-dependent chloride channel; channel conductance-controlling ATPase; ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; CF; ABCC7; TNR-CFTR; |
| Gene ID : | 1080 |
| mRNA Refseq : | NM_000492 |
| Protein Refseq : | NP_000483 |
| MIM : | 602421 |
| UniProt ID : | P13569 |
| Chromosome Location : | 7q31-q32 |
| Pathway : | ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem; |
| Function : | ATP binding; ATP-binding and phosphorylation-dependent chloride channel activity; ATPase activity; PDZ domain binding; channel-conductance-controlling ATPase activity; chloride channel activity; enzyme binding; hydrolase activity; ion channel activity; nucleotide binding; protein binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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